{"id":13629,"date":"2021-10-13T09:31:59","date_gmt":"2021-10-13T08:31:59","guid":{"rendered":"https:\/\/actubusinessangels.com\/?p=13629"},"modified":"2021-10-13T09:31:59","modified_gmt":"2021-10-13T08:31:59","slug":"les-business-angels-des-grandes-ecoles-accompagnent-pep-therapy","status":"publish","type":"post","link":"https:\/\/www.franceangels.org\/en\/article\/les-business-angels-des-grandes-ecoles-accompagnent-pep-therapy\/","title":{"rendered":"Les Business Angels des Grandes Ecoles accompagnent PEP-THERAPY"},"content":{"rendered":"\n

Les Business Angels des Grandes Ecoles<\/a><\/strong> investissent 381 K \u20ac dans la soci\u00e9t\u00e9 PEP-THERAPY<\/a><\/strong>, soci\u00e9t\u00e9 de biotechnologie innovante m\u00e9dicale fond\u00e9e en 2014, qui exploite une technologie de peptides p\u00e9n\u00e9trants et interf\u00e9rents (CP&IP, Cell Penetrating & Interfering Peptides) pour le d\u00e9veloppement de produits th\u00e9rapeutiques ciblant le traitement des cancers.<\/p>\n\n\n\n\n\n\n\n

Cette technologie est issue des r\u00e9sultats de recherche chez Sorbonne Universit\u00e9 et l\u2019Institut Curie. Ces mol\u00e9cules innovantes p\u00e9n\u00e8trent dans la cellule et bloquent sp\u00e9cifiquement, de mani\u00e8re extr\u00eamement cibl\u00e9e, des interactions prot\u00e9ine-prot\u00e9ine cl\u00e9s, inhibant des m\u00e9canismes pathologiques sans alt\u00e9rer les m\u00e9canismes physiologiques.

PEP-THERAPY, a lev\u00e9, entre 2014 et 2019, 3,7 Millions \u20ac pour financer ses essais pr\u00e9-cliniques. En juillet 2021, la soci\u00e9t\u00e9 a boucl\u00e9 un second tour de table de 5,4 M\u20ac pour financer la Phase 1 de ses essais cliniques, dont l\u2019autorisation a \u00e9t\u00e9 d\u00e9livr\u00e9e par l’Agence Nationale de S\u00e9curit\u00e9 du M\u00e9dicament (ANSM) en mars 2021.<\/p>\n\n\n\n

Le r\u00e9seau BADGE a particip\u00e9 \u00e0 cette lev\u00e9e pour 381 K \u20ac aux c\u00f4t\u00e9s des investisseurs historiques, le fonds d\u2019amor\u00e7age Quadrivium 1, g\u00e9r\u00e9 par Seventure Partners, et le Dr Bernard Majoie, Pr\u00e9sident de la Fondation Fournier-Majoie pour l\u2019Innovation (FFMI), ainsi qu\u2019aux cot\u00e9s de la plateforme ANAXAGO, du r\u00e9seau Italian Business  Angels For Growth ( IAG), des fonds d\u2019investissement Doorway, Magna Capital Partners (MCP), et I&I Prague. BPI a accompagn\u00e9 cette lev\u00e9e avec un pr\u00eat de 1,05 Million \u20ac.<\/p>\n\n\n\n

PEP-010, a d\u00e9montr\u00e9 son efficacit\u00e9 antitumorale sur des mod\u00e8les animaux pertinents : il inhibe la croissance de tumeurs primaires humaines de cancer du sein triple n\u00e9gatif et d\u2019ovaire. Les \u00e9tudes de toxicit\u00e9 r\u00e9glementaires sur le rat et le singe ont d\u00e9montr\u00e9 la bonne tol\u00e9rance du produit.
 
L’\u00e9tude clinique, nomm\u00e9e CleverPeptide, est un essai de phase I, en ouvert, non contr\u00f4l\u00e9, multicentrique, en escalade de dose suivie d\u2019une phase d’expansion. Cette \u00e9tude de phase I a \/ b a \u00e9t\u00e9 con\u00e7ue pour \u00e9valuer l’innocuit\u00e9, la tol\u00e9rance, la pharmacocin\u00e9tique et l’activit\u00e9 antitumorale pr\u00e9liminaire de PEP-010 administr\u00e9 par voie intraveineuse, en monoth\u00e9rapie et en association avec le paclitaxel chez les patients atteints de tumeurs solides r\u00e9currentes et\/ou m\u00e9tastatiques, et en particulier dans le cancer du sein triple n\u00e9gatif (TNBC) et le cancer de l’ovaire (OC). Cette \u00e9tude est promue par l’Institut Curie et dirig\u00e9e par le Pr. Christophe Le Tourneau, oncologue \u00e0 l’Institut Curie et chef du d\u00e9partement d\u2019essais cliniques pr\u00e9coces et d\u2019innovation (D3i) de l\u2019Institut Curie, et investigateur principal de l’essai. L’\u00e9tude sera men\u00e9e dans trois centres cliniques : l’Institut Curie, Gustave Roussy et le Centre Fran\u00e7ois Baclesse.
 
Des r\u00e9sultats pr\u00e9liminaires tr\u00e8s encourageants ont \u00e9t\u00e9 obtenus sur des mod\u00e8les cellulaires et, pour chaque indication, les \u00e9quipes \u00e9valuent actuellement les mol\u00e9cules biologiquement actives sur les mod\u00e8les animaux.<\/p>\n\n\n\n

Antoine Prestat, PDG et co-fondateur de PEP-Therapy a d\u00e9clar\u00e9 : \u00abNous sommes ravis d\u2019avoir finalis\u00e9 ce tour de financement via un \u00e9quilibre attractif de fonds dilutifs et non dilutifs provenant de nouveaux investisseurs diversifi\u00e9s et de haute qualit\u00e9 qui apporteront leur expertise et de nouvelles perspectives pour soutenir notre d\u00e9veloppement.\u00bb<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"

Les Business Angels des Grandes Ecoles investissent 381 K \u20ac dans la soci\u00e9t\u00e9 PEP-THERAPY, soci\u00e9t\u00e9 de biotechnologie innovante m\u00e9dicale fond\u00e9e en 2014, qui exploite une technologie de peptides p\u00e9n\u00e9trants et interf\u00e9rents (CP&IP, Cell Penetrating & Interfering Peptides) pour le d\u00e9veloppement de produits th\u00e9rapeutiques ciblant le traitement des cancers.<\/p>\n","protected":false},"author":114,"featured_media":13632,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"inline_featured_image":false},"categories":[155,85],"tags":[670,724],"yoast_head":"\nLes Business Angels des Grandes Ecoles accompagnent PEP-THERAPY - France Angels<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.franceangels.org\/article\/les-business-angels-des-grandes-ecoles-accompagnent-pep-therapy\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Les Business Angels des Grandes Ecoles accompagnent PEP-THERAPY - France Angels\" \/>\n<meta property=\"og:description\" content=\"Les Business Angels des Grandes Ecoles investissent 381 K \u20ac dans la soci\u00e9t\u00e9 PEP-THERAPY, soci\u00e9t\u00e9 de biotechnologie innovante m\u00e9dicale fond\u00e9e en 2014, qui exploite une technologie de peptides p\u00e9n\u00e9trants et interf\u00e9rents (CP&IP, Cell Penetrating & Interfering Peptides) pour le d\u00e9veloppement de produits th\u00e9rapeutiques ciblant le traitement des cancers.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.franceangels.org\/article\/les-business-angels-des-grandes-ecoles-accompagnent-pep-therapy\/\" \/>\n<meta property=\"og:site_name\" content=\"France Angels\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/facebook.com\/france.angels\/\" \/>\n<meta property=\"article:published_time\" content=\"2021-10-13T08:31:59+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.franceangels.org\/wp-content\/uploads\/2021\/10\/pep-therapy.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"900\" \/>\n\t<meta property=\"og:image:height\" content=\"220\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"France Angels\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@franceangels\" \/>\n<meta name=\"twitter:site\" content=\"@franceangels\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"France Angels\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"3 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/www.franceangels.org\/article\/les-business-angels-des-grandes-ecoles-accompagnent-pep-therapy\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/www.franceangels.org\/article\/les-business-angels-des-grandes-ecoles-accompagnent-pep-therapy\/\"},\"author\":{\"name\":\"France Angels\",\"@id\":\"https:\/\/www.franceangels.org\/#\/schema\/person\/23bc1670ad5f0f132d0c3610b1ad2b59\"},\"headline\":\"Les Business Angels des Grandes Ecoles accompagnent PEP-THERAPY\",\"datePublished\":\"2021-10-13T08:31:59+00:00\",\"dateModified\":\"2021-10-13T08:31:59+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/www.franceangels.org\/article\/les-business-angels-des-grandes-ecoles-accompagnent-pep-therapy\/\"},\"wordCount\":574,\"commentCount\":2,\"publisher\":{\"@id\":\"https:\/\/www.franceangels.org\/#organization\"},\"keywords\":[\"Les Business Angels des Grandes Ecoles\",\"PEP-THERAPY\"],\"articleSection\":[\"2021\",\"Closing\"],\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\/\/www.franceangels.org\/article\/les-business-angels-des-grandes-ecoles-accompagnent-pep-therapy\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.franceangels.org\/article\/les-business-angels-des-grandes-ecoles-accompagnent-pep-therapy\/\",\"url\":\"https:\/\/www.franceangels.org\/article\/les-business-angels-des-grandes-ecoles-accompagnent-pep-therapy\/\",\"name\":\"Les Business Angels des Grandes Ecoles accompagnent PEP-THERAPY - France Angels\",\"isPartOf\":{\"@id\":\"https:\/\/www.franceangels.org\/#website\"},\"datePublished\":\"2021-10-13T08:31:59+00:00\",\"dateModified\":\"2021-10-13T08:31:59+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/www.franceangels.org\/article\/les-business-angels-des-grandes-ecoles-accompagnent-pep-therapy\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.franceangels.org\/article\/les-business-angels-des-grandes-ecoles-accompagnent-pep-therapy\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.franceangels.org\/article\/les-business-angels-des-grandes-ecoles-accompagnent-pep-therapy\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Accueil\",\"item\":\"https:\/\/www.franceangels.org\/en\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Les Business Angels des Grandes Ecoles accompagnent PEP-THERAPY\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.franceangels.org\/#website\",\"url\":\"https:\/\/www.franceangels.org\/\",\"name\":\"France Angels\",\"description\":\"F\u00e9d\u00e9ration Nationale des Business Angels\",\"publisher\":{\"@id\":\"https:\/\/www.franceangels.org\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.franceangels.org\/?s={search_term_string}\"},\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/www.franceangels.org\/#organization\",\"name\":\"France Angels\",\"url\":\"https:\/\/www.franceangels.org\/\",\"sameAs\":[\"https:\/\/linkedin.com\/company\/france-angels\",\"https:\/\/www.youtube.com\/channel\/UC5_t1C5xO9AloWjY4o5ob_Q\",\"https:\/\/facebook.com\/france.angels\/\",\"https:\/\/twitter.com\/franceangels\"],\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.franceangels.org\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/www.franceangels.org\/wp-content\/uploads\/2022\/04\/Logo-France-Angels.png\",\"contentUrl\":\"https:\/\/www.franceangels.org\/wp-content\/uploads\/2022\/04\/Logo-France-Angels.png\",\"width\":4033,\"height\":1173,\"caption\":\"France Angels\"},\"image\":{\"@id\":\"https:\/\/www.franceangels.org\/#\/schema\/logo\/image\/\"}},{\"@type\":\"Person\",\"@id\":\"https:\/\/www.franceangels.org\/#\/schema\/person\/23bc1670ad5f0f132d0c3610b1ad2b59\",\"name\":\"France Angels\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.franceangels.org\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/secure.gravatar.com\/avatar\/7686aa9e66054004e747510168483db8?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/secure.gravatar.com\/avatar\/7686aa9e66054004e747510168483db8?s=96&d=mm&r=g\",\"caption\":\"France Angels\"},\"url\":\"https:\/\/www.franceangels.org\/en\/article\/author\/france-angels\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Les Business Angels des Grandes Ecoles accompagnent PEP-THERAPY - France Angels","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.franceangels.org\/article\/les-business-angels-des-grandes-ecoles-accompagnent-pep-therapy\/","og_locale":"en_US","og_type":"article","og_title":"Les Business Angels des Grandes Ecoles accompagnent PEP-THERAPY - France Angels","og_description":"Les Business Angels des Grandes Ecoles investissent 381 K \u20ac dans la soci\u00e9t\u00e9 PEP-THERAPY, soci\u00e9t\u00e9 de biotechnologie innovante m\u00e9dicale fond\u00e9e en 2014, qui exploite une technologie de peptides p\u00e9n\u00e9trants et interf\u00e9rents (CP&IP, Cell Penetrating & Interfering Peptides) pour le d\u00e9veloppement de produits th\u00e9rapeutiques ciblant le traitement des cancers.","og_url":"https:\/\/www.franceangels.org\/article\/les-business-angels-des-grandes-ecoles-accompagnent-pep-therapy\/","og_site_name":"France Angels","article_publisher":"https:\/\/facebook.com\/france.angels\/","article_published_time":"2021-10-13T08:31:59+00:00","og_image":[{"width":900,"height":220,"url":"https:\/\/www.franceangels.org\/wp-content\/uploads\/2021\/10\/pep-therapy.jpg","type":"image\/jpeg"}],"author":"France Angels","twitter_card":"summary_large_image","twitter_creator":"@franceangels","twitter_site":"@franceangels","twitter_misc":{"Written by":"France Angels","Est. reading time":"3 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.franceangels.org\/article\/les-business-angels-des-grandes-ecoles-accompagnent-pep-therapy\/#article","isPartOf":{"@id":"https:\/\/www.franceangels.org\/article\/les-business-angels-des-grandes-ecoles-accompagnent-pep-therapy\/"},"author":{"name":"France Angels","@id":"https:\/\/www.franceangels.org\/#\/schema\/person\/23bc1670ad5f0f132d0c3610b1ad2b59"},"headline":"Les Business Angels des Grandes Ecoles accompagnent PEP-THERAPY","datePublished":"2021-10-13T08:31:59+00:00","dateModified":"2021-10-13T08:31:59+00:00","mainEntityOfPage":{"@id":"https:\/\/www.franceangels.org\/article\/les-business-angels-des-grandes-ecoles-accompagnent-pep-therapy\/"},"wordCount":574,"commentCount":2,"publisher":{"@id":"https:\/\/www.franceangels.org\/#organization"},"keywords":["Les Business Angels des Grandes Ecoles","PEP-THERAPY"],"articleSection":["2021","Closing"],"inLanguage":"en-US","potentialAction":[{"@type":"CommentAction","name":"Comment","target":["https:\/\/www.franceangels.org\/article\/les-business-angels-des-grandes-ecoles-accompagnent-pep-therapy\/#respond"]}]},{"@type":"WebPage","@id":"https:\/\/www.franceangels.org\/article\/les-business-angels-des-grandes-ecoles-accompagnent-pep-therapy\/","url":"https:\/\/www.franceangels.org\/article\/les-business-angels-des-grandes-ecoles-accompagnent-pep-therapy\/","name":"Les Business Angels des Grandes Ecoles accompagnent PEP-THERAPY - France Angels","isPartOf":{"@id":"https:\/\/www.franceangels.org\/#website"},"datePublished":"2021-10-13T08:31:59+00:00","dateModified":"2021-10-13T08:31:59+00:00","breadcrumb":{"@id":"https:\/\/www.franceangels.org\/article\/les-business-angels-des-grandes-ecoles-accompagnent-pep-therapy\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.franceangels.org\/article\/les-business-angels-des-grandes-ecoles-accompagnent-pep-therapy\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/www.franceangels.org\/article\/les-business-angels-des-grandes-ecoles-accompagnent-pep-therapy\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Accueil","item":"https:\/\/www.franceangels.org\/en\/"},{"@type":"ListItem","position":2,"name":"Les Business Angels des Grandes Ecoles accompagnent PEP-THERAPY"}]},{"@type":"WebSite","@id":"https:\/\/www.franceangels.org\/#website","url":"https:\/\/www.franceangels.org\/","name":"France Angels","description":"F\u00e9d\u00e9ration Nationale des Business Angels","publisher":{"@id":"https:\/\/www.franceangels.org\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.franceangels.org\/?s={search_term_string}"},"query-input":"required name=search_term_string"}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/www.franceangels.org\/#organization","name":"France Angels","url":"https:\/\/www.franceangels.org\/","sameAs":["https:\/\/linkedin.com\/company\/france-angels","https:\/\/www.youtube.com\/channel\/UC5_t1C5xO9AloWjY4o5ob_Q","https:\/\/facebook.com\/france.angels\/","https:\/\/twitter.com\/franceangels"],"logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.franceangels.org\/#\/schema\/logo\/image\/","url":"https:\/\/www.franceangels.org\/wp-content\/uploads\/2022\/04\/Logo-France-Angels.png","contentUrl":"https:\/\/www.franceangels.org\/wp-content\/uploads\/2022\/04\/Logo-France-Angels.png","width":4033,"height":1173,"caption":"France Angels"},"image":{"@id":"https:\/\/www.franceangels.org\/#\/schema\/logo\/image\/"}},{"@type":"Person","@id":"https:\/\/www.franceangels.org\/#\/schema\/person\/23bc1670ad5f0f132d0c3610b1ad2b59","name":"France Angels","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.franceangels.org\/#\/schema\/person\/image\/","url":"https:\/\/secure.gravatar.com\/avatar\/7686aa9e66054004e747510168483db8?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/7686aa9e66054004e747510168483db8?s=96&d=mm&r=g","caption":"France Angels"},"url":"https:\/\/www.franceangels.org\/en\/article\/author\/france-angels\/"}]}},"_links":{"self":[{"href":"https:\/\/www.franceangels.org\/en\/wp-json\/wp\/v2\/posts\/13629"}],"collection":[{"href":"https:\/\/www.franceangels.org\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.franceangels.org\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.franceangels.org\/en\/wp-json\/wp\/v2\/users\/114"}],"replies":[{"embeddable":true,"href":"https:\/\/www.franceangels.org\/en\/wp-json\/wp\/v2\/comments?post=13629"}],"version-history":[{"count":0,"href":"https:\/\/www.franceangels.org\/en\/wp-json\/wp\/v2\/posts\/13629\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.franceangels.org\/en\/wp-json\/wp\/v2\/media\/13632"}],"wp:attachment":[{"href":"https:\/\/www.franceangels.org\/en\/wp-json\/wp\/v2\/media?parent=13629"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.franceangels.org\/en\/wp-json\/wp\/v2\/categories?post=13629"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.franceangels.org\/en\/wp-json\/wp\/v2\/tags?post=13629"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}