{"id":13947,"date":"2021-12-06T15:03:29","date_gmt":"2021-12-06T14:03:29","guid":{"rendered":"https:\/\/actubusinessangels.com\/?p=13947"},"modified":"2021-12-06T15:03:29","modified_gmt":"2021-12-06T14:03:29","slug":"peptinov-leve-des-fonds-aupres-des-business-angels-des-grandes-ecoles","status":"publish","type":"post","link":"https:\/\/www.franceangels.org\/en\/article\/peptinov-leve-des-fonds-aupres-des-business-angels-des-grandes-ecoles\/","title":{"rendered":"Peptinov l\u00e8ve des fonds aupr\u00e8s des Business Angels des Grandes Ecoles"},"content":{"rendered":"\n

Les Business Angels des Grandes Ecoles<\/a><\/strong> investissent 110 K \u20ac lors de la deuxi\u00e8me lev\u00e9e de fonds r\u00e9alis\u00e9e par Peptinov<\/a><\/strong>, start-up bas\u00e9e sur le site d\u2019incubation de l\u2019h\u00f4pital Cochin, sp\u00e9cialiste du traitement des maladies inflammatoires chroniques telle que l\u2019arthrose, et qui d\u00e9veloppe un vaccin pour pr\u00e9venir ces pathologies.<\/p>\n\n\n\n\n\n\n\n

Cr\u00e9\u00e9e fin 2009 et issue des travaux du Pr. Jean-Fran\u00e7ois Zagury (Cnam, Paris), Peptinov vient de cl\u00f4turer une lev\u00e9e de fonds de 2,7m\u20ac. Les participants \u00e0 ce tour comprennent des Business Angels parmi lesquels BADGE, le groupe de pr\u00e9voyance IRCEM, Happy Capital (crowdfunding), et la soci\u00e9t\u00e9 FCB, holding d\u00e9tenant 53% du groupe C\u00e9g\u00e9dim. Cette lev\u00e9e permettra \u00e0 Peptinov de r\u00e9aliser son premier essai clinique de phase 1 chez des patients atteints d\u2019arthrose inflammatoire du genou.

Peptinov a pour ambition de r\u00e9volutionner le traitement des maladies inflammatoires chroniques, en particulier de l\u2019arthrose inflammatoire, par une strat\u00e9gie innovante d\u2019immunoth\u00e9rapie active. Cette approche vise \u00e0 induire la production d\u2019anticorps par les patients eux-m\u00eames, afin de r\u00e9guler le niveau de prot\u00e9ines du soi dont la surproduction peut avoir un effet pathog\u00e8ne. Il est d\u00e9sormais av\u00e9r\u00e9 que dans un tr\u00e8s grand nombre de cas d\u2019arthrose, des processus inflammatoires jouent un r\u00f4le majeur dans la progression de la maladie. Une prot\u00e9ine appel\u00e9e IL-6 peut, lorsqu\u2019elle est surproduite, agir en v\u00e9ritable amplificateur de l\u2019inflammation, et par voie de cons\u00e9quence de la d\u00e9gradation du cartilage.

Enjeu de sant\u00e9 publique majeur, l\u2019arthrose touche pr\u00e8s de 250 millions de personnes dans le monde et repr\u00e9sente une consultation m\u00e9dicale sur 4 en France. Il n\u2019existe \u00e0 ce jour aucun traitement curatif.

Peptinov m\u00e8ne actuellement \u00e0 l\u2019h\u00f4pital Cochin (Paris) un essai clinique de phase 1 chez 24 patients atteints d\u2019arthrose inflammatoire du genou, devant se terminer fin 2022. Cet essai vise en particulier \u00e0 \u00e9tablir la bonne tol\u00e9rance de l\u2019immunoth\u00e9rapie anti-IL-6 de Peptinov chez l\u2019homme.  

\u00ab L\u2019exc\u00e8s d\u2019IL-6 et l\u2019inflammation chronique sont impliqu\u00e9s dans de nombreuses pathologies, notamment celles du vieillissement<\/em>. \u00bb, explique Ren\u00e9 Azoulai, CEO de Peptinov, qui pr\u00e9cise \u00ab Nous pensons qu\u2019en agissant \u00e0 des stades pr\u00e9coces et en utilisant les ressources de notre corps, nous pourrions pr\u00e9venir les effets n\u00e9fastes de cette inflammation, et ce par un traitement disposant de r\u00e9els avantages en termes de co\u00fbts et de simplicit\u00e9 d\u2019administration<\/em>. \u00bb \u00c0 la suite de ce premier essai, Peptinov r\u00e9alisera en 2023-2024 des essais cliniques de phase II dans diff\u00e9rentes indications, y compris l\u2019arthrose inflammatoire, qui seront financ\u00e9s par une lev\u00e9e de fonds institutionnelle<\/p>\n","protected":false},"excerpt":{"rendered":"

Les Business Angels des Grandes Ecoles investissent 110 K \u20ac lors de la deuxi\u00e8me lev\u00e9e de fonds r\u00e9alis\u00e9e par Peptinov, start-up bas\u00e9e sur le site d\u2019incubation de l\u2019h\u00f4pital Cochin, sp\u00e9cialiste du traitement des maladies inflammatoires chroniques telle que l\u2019arthrose, et qui d\u00e9veloppe un vaccin pour pr\u00e9venir ces pathologies.<\/p>\n","protected":false},"author":114,"featured_media":13952,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"inline_featured_image":false},"categories":[155,85],"tags":[109,75,748],"yoast_head":"\nPeptinov l\u00e8ve des fonds aupr\u00e8s des Business Angels des Grandes Ecoles - France Angels<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.franceangels.org\/article\/peptinov-leve-des-fonds-aupres-des-business-angels-des-grandes-ecoles\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Peptinov l\u00e8ve des fonds aupr\u00e8s des Business Angels des Grandes Ecoles - 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