{"id":17492,"date":"2023-10-25T14:44:17","date_gmt":"2023-10-25T13:44:17","guid":{"rendered":"https:\/\/actubusinessangels.com\/?p=17492"},"modified":"2023-10-25T14:44:17","modified_gmt":"2023-10-25T13:44:17","slug":"des-reseaux-de-business-angels-renouvellent-leur-soutien-a-seabelife","status":"publish","type":"post","link":"https:\/\/www.franceangels.org\/en\/article\/des-reseaux-de-business-angels-renouvellent-leur-soutien-a-seabelife\/","title":{"rendered":"Des r\u00e9seaux de Business Angels renouvellent leur soutien \u00e0 SeaBeLife"},"content":{"rendered":"\n

SeaBeLife<\/a><\/strong>, soci\u00e9t\u00e9 de biotechnologie sp\u00e9cialis\u00e9e dans le d\u00e9veloppement de candidats-m\u00e9dicaments destin\u00e9s \u00e0 bloquer la n\u00e9crose cellulaire, l\u00e8ve 1,2M\u20ac de financement compl\u00e9mentaire au tour d\u2019amor\u00e7age aupr\u00e8s du fonds iXLife et des r\u00e9seaux de business angels historiques ayant d\u00e9j\u00e0 particip\u00e9 au financement de la soci\u00e9t\u00e9 : Breizh Angels<\/strong>, Angels Sant\u00e9<\/a><\/strong>, WeLike<\/a><\/strong>, Les Business Angels des Grandes Ecoles<\/a><\/strong> et Investessor<\/a><\/strong>.<\/p>\n\n\n\n\n\n\n\n

Suite \u00e0 ce tour de financement, le Dr Kinet, Pr\u00e9sident d\u2019iXLife, rejoint le comit\u00e9 strat\u00e9gique de SeaBeLife. La soci\u00e9t\u00e9 avait lev\u00e9 1,6 million d\u2019euros en amor\u00e7age depuis 2020 aupr\u00e8s des business angels.<\/p>\n\n\n\n

SeaBeLife est une entreprise de biotechnologie sp\u00e9cialis\u00e9e dans le d\u00e9veloppement de candidats m\u00e9dicaments first in class destin\u00e9s \u00e0 bloquer la mort cellulaire par n\u00e9crose r\u00e9gul\u00e9e afin de prot\u00e9ger ou r\u00e9g\u00e9n\u00e9rer les organes affect\u00e9s par des pathologies s\u00e9v\u00e8res sans alternative th\u00e9rapeutique efficace.
La soci\u00e9t\u00e9 cible en premier lieu les pathologies aigu\u00ebs du foie (h\u00e9patites aigu\u00ebs et h\u00e9patites fulminantes), notamment l\u2019intoxication au parac\u00e9tamol, tout en poursuivant son travail sur la DMLA, la maladie de Parkinson et les autres maladies neurod\u00e9g\u00e9n\u00e9ratives (dont Alzheimer).<\/p>\n\n\n\n

La technologie de plateforme de SeaBeLife repose sur un portefeuille de plus de 150 mol\u00e9cules pertinentes actives biologiquement, ayant la sp\u00e9cificit\u00e9 unique d\u2019inhiber deux formes de mort cellulaire r\u00e9gul\u00e9e activ\u00e9es dans des conditions pathologiques : la n\u00e9croptose et la ferroptose. Les applications de ces mol\u00e9cules sont prot\u00e9g\u00e9es par cinq familles de brevets. Deux actifs sont en cours de d\u00e9veloppement pr\u00e9clinique : SBL01 pour traiter les h\u00e9patites s\u00e9v\u00e8res pour lequel SeaBeLife a obtenu des preuves de concept in vivo convaincant e s et doit d\u00e9marrer le d\u00e9veloppement clinique en 2024 ; et SBL02 pour pr\u00e9venir la perte de vision chez les patients atteints de DMLA s\u00e8che, pour lequel la soci\u00e9t\u00e9 a obtenu de s POC in vivo pr\u00e9liminaires.<\/p>\n\n\n\n

Cette lev\u00e9e de fonds va permettre \u00e0 la soci\u00e9t\u00e9 de financer le d\u00e9veloppement r\u00e9glementaire de ses candidats-m\u00e9dicament, notamment dans les pathologies aigu\u00ebs du foie et les pathologies oculaires en s\u2019appuyant sur sa technologie brevet\u00e9e unique ciblant deux voies de mort cellulaire r\u00e9gul\u00e9e. Les fonds permettront \u00e9galement d\u2019\u00e9toffer l\u2019\u00e9quipe avec l\u2019embauche de plusieurs sp\u00e9cialistes de haut niveau pour pr\u00e9parer les essais cliniques. Une phase I dans les h\u00e9patites s\u00e9v\u00e8res devrait d\u00e9marrer en 2024. La soci\u00e9t\u00e9 travaille \u00e9galement au renforcement de ses partenariats strat\u00e9giques, en particulier avec les industriels pharmaceutiques dans les pathologies oculaires et \u00e0 l\u2019optimisation de ses candidats-m\u00e9dicaments pour adresser les maladies neurod\u00e9g\u00e9n\u00e9ratives d\u2019ici 2025.<\/p>\n","protected":false},"excerpt":{"rendered":"

SeaBeLife, soci\u00e9t\u00e9 de biotechnologie sp\u00e9cialis\u00e9e dans le d\u00e9veloppement de candidats-m\u00e9dicaments destin\u00e9s \u00e0 bloquer la n\u00e9crose cellulaire, l\u00e8ve 1,2M\u20ac de financement compl\u00e9mentaire au tour d\u2019amor\u00e7age aupr\u00e8s du fonds iXLife et des r\u00e9seaux de business angels historiques ayant d\u00e9j\u00e0 particip\u00e9 au financement de la soci\u00e9t\u00e9 : Breizh Angels, Angels Sant\u00e9, WeLike, Les Business Angels des Grandes Ecoles…<\/p>\n","protected":false},"author":114,"featured_media":17497,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"inline_featured_image":false},"categories":[162,85,86],"tags":[147,256,63,111,670,75,691,1084],"yoast_head":"\nDes r\u00e9seaux de Business Angels renouvellent leur soutien \u00e0 SeaBeLife - France Angels<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.franceangels.org\/article\/des-reseaux-de-business-angels-renouvellent-leur-soutien-a-seabelife\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Des r\u00e9seaux de Business Angels renouvellent leur soutien \u00e0 SeaBeLife - 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