{"id":25900,"date":"2026-05-25T14:33:56","date_gmt":"2026-05-25T12:33:56","guid":{"rendered":"https:\/\/www.franceangels.org\/?p=25900"},"modified":"2026-05-25T14:38:22","modified_gmt":"2026-05-25T12:38:22","slug":"femmes-business-angels-accompagne-hephaistos","status":"publish","type":"post","link":"https:\/\/www.franceangels.org\/en\/article\/femmes-business-angels-accompagne-hephaistos\/","title":{"rendered":"Femmes Business Angels accompagne Hepha\u00efstos"},"content":{"rendered":"\n<p><strong><a href=\"https:\/\/femmesbusinessangels.org\/\" target=\"_blank\" rel=\"noreferrer noopener\">Femmes Business Angels<\/a><\/strong> a de nouveau particip\u00e9 \u00e0 la nouvelle lev\u00e9e de fonds d\u2019<strong><a href=\"https:\/\/hephaistos-pharma.fr\/\" target=\"_blank\" rel=\"noreferrer noopener\">Hepha\u00efstos<\/a><\/strong>, une <strong>startup biotech d\u00e9veloppant une immunoth\u00e9rapie anti-cancer intraveineuse ciblant les tumeurs froides<\/strong>.<\/p>\n\n\n\n<p>Fond\u00e9e par <strong><a href=\"https:\/\/www.linkedin.com\/in\/frederic-caroff\/\" target=\"_blank\" rel=\"noreferrer noopener\">Fr\u00e9d\u00e9ric CAROFF<\/a><\/strong>, la soci\u00e9t\u00e9 d\u00e9veloppe un agoniste TLR4 d\u00e9toxifi\u00e9 actuellement en phase pr\u00e9clinique avanc\u00e9e, avec l\u2019ambition d\u2019ouvrir de nouvelles perspectives th\u00e9rapeutiques sur des cancers aujourd\u2019hui difficiles \u00e0 traiter.<\/p>\n\n\n\n<p>Son principal candidat-m\u00e9dicament, HEPHA 440, a d\u00e9montr\u00e9 une activit\u00e9 antitumorale prometteuse dans un large \u00e9ventail de mod\u00e8les pr\u00e9cliniques de cancers, aussi bien en monoth\u00e9rapie qu&#8217;en association avec d&#8217;autres immunoth\u00e9rapies. Ce m\u00e9dicament a \u00e9galement d\u00e9montr\u00e9 une bonne tol\u00e9rance et une large marge th\u00e9rapeutique, laissant pr\u00e9sager une administration syst\u00e9mique s\u00fbre et efficace chez l&#8217;homme.<\/p>\n\n\n\n<p>Les essais cliniques de HEPHA 440 devraient d\u00e9buter en 2027.<\/p>\n\n\n\n<p>Ce financement a permis de r\u00e9unir 90 K\u20ac, illustrant l\u2019int\u00e9r\u00eat des membres de Femmes Business Angels pour des projets deeptech \u00e0 fort impact m\u00e9dical et scientifique.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Femmes Business Angels a de nouveau particip\u00e9 \u00e0 la nouvelle lev\u00e9e de fonds d\u2019Hepha\u00efstos, une startup biotech d\u00e9veloppant une immunoth\u00e9rapie anti-cancer intraveineuse ciblant les tumeurs froides. Fond\u00e9e par Fr\u00e9d\u00e9ric CAROFF, la soci\u00e9t\u00e9 d\u00e9veloppe un agoniste TLR4 d\u00e9toxifi\u00e9 actuellement en phase pr\u00e9clinique avanc\u00e9e, avec l\u2019ambition d\u2019ouvrir de nouvelles perspectives th\u00e9rapeutiques sur des cancers aujourd\u2019hui difficiles \u00e0&hellip;<\/p>\n","protected":false},"author":4,"featured_media":25904,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"inline_featured_image":false},"categories":[1711,85],"tags":[94,1860,75],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v19.7.2 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Femmes Business Angels accompagne Hepha\u00efstos - France Angels<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.franceangels.org\/article\/femmes-business-angels-accompagne-hephaistos\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Femmes Business Angels accompagne Hepha\u00efstos - France Angels\" \/>\n<meta property=\"og:description\" content=\"Femmes Business Angels a de nouveau particip\u00e9 \u00e0 la nouvelle lev\u00e9e de fonds d\u2019Hepha\u00efstos, une startup biotech d\u00e9veloppant une immunoth\u00e9rapie anti-cancer intraveineuse ciblant les tumeurs froides. Fond\u00e9e par Fr\u00e9d\u00e9ric CAROFF, la soci\u00e9t\u00e9 d\u00e9veloppe un agoniste TLR4 d\u00e9toxifi\u00e9 actuellement en phase pr\u00e9clinique avanc\u00e9e, avec l\u2019ambition d\u2019ouvrir de nouvelles perspectives th\u00e9rapeutiques sur des cancers aujourd\u2019hui difficiles \u00e0&hellip;\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.franceangels.org\/article\/femmes-business-angels-accompagne-hephaistos\/\" \/>\n<meta property=\"og:site_name\" content=\"France Angels\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/facebook.com\/france.angels\/\" \/>\n<meta property=\"article:published_time\" content=\"2026-05-25T12:33:56+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2026-05-25T12:38:22+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.franceangels.org\/wp-content\/uploads\/2026\/05\/Visuels-articles-7.png\" \/>\n\t<meta property=\"og:image:width\" content=\"1633\" \/>\n\t<meta property=\"og:image:height\" content=\"805\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"author\" content=\"sylvain Godard\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@franceangels\" \/>\n<meta name=\"twitter:site\" content=\"@franceangels\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"sylvain Godard\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/www.franceangels.org\/article\/femmes-business-angels-accompagne-hephaistos\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/www.franceangels.org\/article\/femmes-business-angels-accompagne-hephaistos\/\"},\"author\":{\"name\":\"sylvain Godard\",\"@id\":\"https:\/\/www.franceangels.org\/#\/schema\/person\/648593124b8eaf770f4db2940aaecf95\"},\"headline\":\"Femmes Business Angels accompagne Hepha\u00efstos\",\"datePublished\":\"2026-05-25T12:33:56+00:00\",\"dateModified\":\"2026-05-25T12:38:22+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/www.franceangels.org\/article\/femmes-business-angels-accompagne-hephaistos\/\"},\"wordCount\":179,\"publisher\":{\"@id\":\"https:\/\/www.franceangels.org\/#organization\"},\"keywords\":[\"Femmes Business Angels\",\"Hepha\u00efstos\",\"Lev\u00e9e de fonds\"],\"articleSection\":[\"2026\",\"Closing\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.franceangels.org\/article\/femmes-business-angels-accompagne-hephaistos\/\",\"url\":\"https:\/\/www.franceangels.org\/article\/femmes-business-angels-accompagne-hephaistos\/\",\"name\":\"Femmes Business Angels accompagne Hepha\u00efstos - 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